Article

Nephrotic syndrome and glomerular basement membrane : genetic defect of the laminin α5 chain

2018-01-01

Abstract excerpt

Nephrotic syndrome is a heterogeneous group of disorders characterised by renal and extra-renal manifestations. Classic symptoms of nephrotic syndrome include severe proteinuria, hypoalbumiaemia, oedema and hyperlipidaemia. Genetic studies of hereditary forms of nephrotic syndrome have led to the identification of proteins playing a crucial role in slit diaphragm signalling, regulation of actin cytoskeleton dynami...

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Literature Corpus work: 20396392-7efd-55ce-8385-1ce998863079
DOI: 10.21954/ou.ro.0000dafc

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