Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alport syndrome and Pierson syndrome: Diseases of the glomerular basement membrane.

Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2018

Funk Steven D, Lin Meei-Hua, Miner Jeffrey H

Abstract excerpt

The glomerular basement membrane (GBM) is an important component of the kidney's glomerular filtration barrier. Like all basement membranes, the GBM contains type IV collagen, laminin, nidogen, and heparan sulfate proteoglycan. It is flanked by the podocytes and glomerular endothelial cells that both synthesize it and adhere to it. Mutations that affect the GBM's collagen α3α4α5(IV) components cause Alport...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abnormalities, Multiple
Share to Collagen Type IV

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Eye Abnormalities

Share to Glomerular Basement Membrane

Share to Laminin

Share to Myasthenic Syndromes, Congenital

Share to Nephritis, Hereditary

Share to Nephrotic Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 29673759
DOI: 10.1016/j.matbio.2018.04.008
PMCID: PMC6146048

Genes

LAMB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alport syndrome and Pierson syndrome: Diseases of the glomerular basement membrane.PMID 29673759Read ↗

Inherited diseases of the glomerular basement membrane.Semantic proximity Read ↗

Glomerular basement membrane and related glomerular disease.Semantic proximity Read ↗

The Renal Lesions of Alport SyndromeSemantic proximity Read ↗

Alport syndrome: a unified classification of genetic disorders of collagen IV α345: a position paper of the Alport Syndrome Classification Working Group.Semantic proximity Read ↗

Molecular Basis, Diagnostic Challenges and Therapeutic Approaches of Alport Syndrome: A Primer for CliniciansSemantic proximity Read ↗

A comparison of the ocular features in Pierson and Alport syndrome: a case report and literature review.Semantic proximity Read ↗

Alport syndrome and Alport kidney diseases - elucidating the disease spectrum.Semantic proximity Read ↗

The glomerular basement membrane as a barrier to albumin.Semantic proximity Read ↗

Five-Year Follow-Up and Successful Kidney Transplantation in a Girl with a Severe Phenotype of Pierson Syndrome.Semantic proximity Read ↗

Genetic disorders of glomerular basement membranes.Semantic proximity Read ↗

Collagen IV diseases: A focus on the glomerular basement membrane in Alport syndrome.Semantic proximity Read ↗

Collagen Genes-Related Glomerular Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.