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Article

Peptide Aptamer sP10 Targeting NPM1 Attenuates Liver Fibrosis and Hepatocellular Carcinoma

2026-02-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective</bold> : Liver fibrosis and hepatocellular carcinoma (HCC) are interrelated diseases with high global mortality rates and limited therapeutic options. This study aimed to develop a dual-targeting therapeutic agent against both fibrogenesis and hepatocarcinogenesis by targeting nucleophosmin (NPM1), a multifunctional nucleolar protein overexpressed in activated hepatic...

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Literature Corpus work
20278fcf-4e20-5d18-9c95-3a59fc0fba1d
DOI
10.21203/rs.3.rs-8746134/v1
Open publication

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Peptide Aptamer sP10 Targeting NPM1 Attenuates Liver Fibrosis and Hepatocellular CarcinomaDOI 10.21203/rs.3.rs-8746134/v1
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