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CRISPR Screen Contributes to Novel Target Discovery in Prostate Cancer

26 Nov 2021

Abstract excerpt

Prostate cancer (PCa) is one of the common malignancies in male adults. Recent advances in omics technology, especially in next-generation sequencing, have increased the opportunity to identify genes that correlate with cancer diseases, including PCa. In addition, a genetic screen based on CRISPR/Cas9 technology has elucidated the mechanisms of cancer progression and drug resistance, which in turn has enabled the...

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PMID: 34884583
DOI: 10.3390/ijms222312777

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