Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

15 Nov 2010

Abstract excerpt

Throughout most of pregnancy, uterine quiescence is maintained by increased progesterone receptor (PR) transcriptional activity, whereas spontaneous labor is initiated/facilitated by a concerted series of biochemical events that activate inflammatory pathways and have a negative impact on PR function. In this study, we uncovered a previously undescribed regulatory pathway whereby micro-RNAs (miRNAs) serve as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pregnancy and preeclampsia studies
Share to Preterm Birth and Chorioamnionitis
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21079000
DOI: 10.1073/pnas.1008301107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and laborPMID 21079000Read ↗

Multifactorial Regulation of Myometrial Contractility During Pregnancy and ParturitionSemantic proximity Read ↗

miR-200 Regulates Endometrial Development During Early PregnancySemantic proximity Read ↗

Mice lacking uterine enhancer of zeste homolog 2 have transcriptomic changes associated with uterine epithelial proliferation.Semantic proximity Read ↗

Myometrial progesterone receptor determines a transcription program for uterine remodeling and contractions during pregnancySemantic proximity Read ↗

Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1α, POU/OCT, and NF-κBSemantic proximity Read ↗

TGFβ superfamily signaling and uterine decidualizationSemantic proximity Read ↗

Molecular Basis of Impaired Decidualization in the Eutopic Endometrium of Endometriosis PatientsSemantic proximity Read ↗

Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesisSemantic proximity Read ↗

Integral Roles of the TGFβ Signaling Pathway in Uterine Function and DiseaseSemantic proximity Read ↗

Integrative Analyses of Uterine Transcriptome and MicroRNAome Reveal Compromised LIF-STAT3 Signaling and Progesterone Response in the Endometrium of Patients with Recurrent/Repeated Implantation Failure (RIF)Semantic proximity Read ↗

The EZH2–PRC2–H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasionSemantic proximity Read ↗

Illuminating the “Black Box” of Progesterone-Dependent Embryo Implantation Using Engineered MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.