Article

Investigation of the Impact of Clonal Hematopoiesis on Severity and Pathophysiology of COVID-19 in Rhesus Macaques

2023-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Clinical manifestations of COVID-19 vary widely, ranging from asymptomatic to severe respiratory failure with profound inflammation. Although risk factors for severe illness have been identified, definitive determinants remain elusive. Clonal hematopoiesis (CH), the expansion of hematopoietic stem and progenitor cells bearing acquired somatic mutations, is associated with advanced age and hyperi...

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Literature Corpus work: 1fed4a85-b920-5d13-9a8e-c04196823a47
DOI: 10.1101/2023.01.01.522064

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