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IGF-2 modified by the m6A demethylation enzyme ALKBH5 in the ossification of the ligamentum flavum

2021-04-13

Abstract excerpt

Abstract Background: Ossification of the ligamentum flavum (OLF) is a pathological heterotopic ossification of the paravertebral ligament. However, the specific pathophysiology mechanism of this disease is still unknown. The m 6 A methylation and its potential functions in OLF remain to be unexplored. <h4>Method:</h4> In this study, we performed a transcriptome-wide methylation analysis using the OLF and normal li...

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Literature Corpus work
1f8cfdf1-e171-5166-b518-cd01a9afbd8d
DOI
10.21203/rs.3.rs-399010/v1
Open publication

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IGF-2 modified by the m6A demethylation enzyme ALKBH5 in the ossification of the ligamentum flavumDOI 10.21203/rs.3.rs-399010/v1
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