Article
Integrated bioinformatic analysis of the shared mechanisms in endochondral ossification Between ossification of the ligamentum flavum (OLF) and ankylosing spondylitis (AS)
2023-10-18
Abstract excerpt
Ossification of the ligamentum flavum (OLF) and ankylosing spondylitis (AS) are complex maladies characterized by the progressive process of endochondral ossification. This study aims to elucidate shared biomarkers related to ectopic ossification and the potential molecular regulatory mechanism. Microarray and RNA-seq datasets, obtained from the Gene Expression Omnibus (GEO) database, were utilized to discern diff...
Topics
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- Heterotopic Ossification and Related Conditions
- Hypertrophic osteoarthropathy and related conditions
- Osteoarthritis Treatment and Mechanisms
- Rheumatoid Arthritis Research and Therapies
- Single-cell and spatial transcriptomics
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- vaccines and immunoinformatics approaches
Identifiers and source
- Literature Corpus work
- af99d2b9-cdba-54f2-b858-1e6ac9f628d2
- DOI
- 10.21203/rs.3.rs-3440201/v1
