Article

Archaic introgression contributed to shape the adaptive modulation of angiogenesis and cardiovascular traits in human high-altitude populations from the Himalayas

2023-05-25

Abstract excerpt

It is well established that several Homo Sapiens populations experienced admixture with extinct human species during their evolutionary history. Sometimes, such a gene flow could have played a role in modulating their capability to cope with a variety of selective pressures, thus resulting in archaic adaptive introgression events. A paradigmatic example of this evolutionary mechanism is offered by the EPAS1 gene...

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Literature Corpus work: 1f2eb395-4924-596c-994c-bae1d46d5f44
DOI: 10.1101/2023.05.23.540768

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