Article

Deciphering the gene regulatory circuitry governing chemoresistance in Triple-Negative Breast Cancer

2023-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, due in part to extensive intratumoral heterogeneity, high rates of metastasis and chemoresistance, leading to poor clinical outcomes. Despite progress, the mechanistic basis of chemotherapy resistance in TNBC patients remains poorly understood. Here, using single-cell transcriptome datasets of matched longitudinal...

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Literature Corpus work: 1f212d8b-ef17-5630-9a73-8e5744d046bb
DOI: 10.1101/2023.05.05.539623

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