Article

Rapid and cost-effective development of stable clones for the production of anti-Ebola monoclonal antibodies in HEK293T cells

2020-04-23

Abstract excerpt

The Ebola virus (EBOV) disease has caused serious and recurrent epidemics in recent years, resulting in a fatality rate of nearly 50%. The most effective experimental therapy against the EBOV is the use of monoclonal antibodies (mAbs). In this work, we describe the development of HEK293T cells engineered for the transient and stable expression of mAb13C6, a neutralizing anti-EBOV monoclonal antibody. We transfecte...

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Literature Corpus work: 1ea00e25-70f8-53bf-921d-7aa9a10a9f9e
DOI: 10.1101/2020.04.21.054429

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