Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex

10 May 2018

Abstract excerpt

Human herpesvirus 8 (HHV-8) is causally related to human malignancies. HHV-8 latent viral FLICE-inhibitory protein (vFLIP) is a viral oncoprotein that is linked to pathogenesis, but how its expression is regulated is largely unknown. In an attempt to understand the role of the mitochondrial antiviral signaling (MAVS) adaptor in HHV-8 infection, we discovered that vFLIP expression was post-translationally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to interferon and immune responses
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29746593
DOI: 10.1371/journal.ppat.1007058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complexPMID 29746593Read ↗

Activation of NIX-mediated mitophagy and replication by an interferon regulatory factor homologue of human herpesvirusSemantic proximity Read ↗

Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirusSemantic proximity Read ↗

Modulation of Mitochondrial Antiviral Signaling by Human Herpesvirus 8 Interferon Regulatory Factor 1Semantic proximity Read ↗

Induction of IL-8 expression by human herpesvirus 8 encoded vFLIP K13 via NF-κB activationSemantic proximity Read ↗

Flavivirus Infection Impairs Peroxisome Biogenesis and Early Antiviral SignalingSemantic proximity Read ↗

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylationSemantic proximity Read ↗

The mitophagy receptor NIX induces vIRF-1 oligomerization and interaction with GABARAPL1 for the promotion of HHV-8 reactivation-induced mitophagySemantic proximity Read ↗

Global Lipidomic Analysis of Lytic KSHV Infection: The lipid chaperone FABP4 is required for maximal infectious virion productionSemantic proximity Read ↗

SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITASemantic proximity Read ↗

Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolismSemantic proximity Read ↗

Kaposi’s sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral productionSemantic proximity Read ↗

Understanding Metabolic Pathway Rewiring by Oncogenic Gamma HerpesvirusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.