Mapping Inter-Metabolite Relationships in the Human Brain: A Multi-Site, Multi-Modal MRS Study

Abstract excerpt

Technological advances in magnetic resonance spectroscopy (MRS), particularly at ultra-high field strengths (e.g., 7T), now allow for the reliable quantification of an increasing number of brain metabolites across multiple brain regions. How-ever, most studies remain constrained to analyses of isolated metabolite levels, overlooking the complex interdependencies that govern neurometabolic regula-tion. Here, we pre...

Topics

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• Brain
• Follow-Up Studies
• Gene Expression
• Gene Regulatory Networks
• Magnetic Resonance Imaging
• Neural Pathways
• Phenotype
• Radiography

Identifiers and source

Literature Corpus work

1e26d5ec-ec29-5430-8834-b0065e884c09

DOI

10.1101/2025.11.17.25340250