Article

Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 Individuals

2020-12-11

Abstract excerpt

The newly emerged and rapidly spreading SARS-CoV-2 causes coronavirus disease 2019 (COVID-19). To facilitate a deeper understanding of the viral biology we developed a capture sequencing methodology to generate SARS-CoV-2 genomic and transcriptome sequences from infected patients. We utilized an oligonucleotide probe-set representing the full-length genome to obtain both genomic and transcriptome (subgenomic open...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1e159599-7ade-52de-a2aa-abc90e82081a
DOI: 10.1101/2020.12.11.421057

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 IndividualsDOI 10.1101/2020.12.11.421057Read

Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individualsSemantic proximity Read

Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals.Semantic proximity Read

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotypingSemantic proximity Read

Highly multiplexed oligonucleotide probe-ligation testing enables efficient extraction-free SARS-CoV-2 detection and viral genotyping.Semantic proximity Read

High-coverage SARS-CoV-2 genome sequences acquired by target capture sequencing.Semantic proximity Read

SARS-CoV-2 genome diversity at the binding sites of oligonucleotides used for COVID-19 diagnosisSemantic proximity Read

A High-Coverage SARS-CoV-2 Genome Sequence Acquired by Target Capture SequencingSemantic proximity Read

Complete Genomic Characterization of Global Pathogens, Respiratory Syncytial Virus (RSV), and Human Norovirus (HuNoV) Using Probe-based Capture EnrichmentSemantic proximity Read

Targeted Hybridization Capture of SARS-CoV-2 and Metagenomics Enables Genetic Variant Discovery and Nasal Microbiome Insights.Semantic proximity Read

Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon AntagonismSemantic proximity Read

Capturing SARS-CoV-2 from patient samples with low viral abundance: a comparative analysisSemantic proximity Read

SARS-CoV-2 genomes recovered by long amplicon tiling multiplex approach using nanopore sequencing and applicable to other sequencing platformsSemantic proximity Read