Article

Hypoxia Activates SUMO-1-HIF-1α Signaling Pathway to Upregulate Pro-inflammatory Cytokines and Permeability in Human Tonsil Epithelial Cells

2021-02-04

Abstract excerpt

<title>Abstract</title> <p>Adenoid hypertrophy (AH) can cause harmful effects on untreated children, which include mouth breathing, chronic intermittent hypoxia, sleep disordered breathing (SDB), and even some behavioral problems. However, the molecular mechanisms underlying this pathophysiological process have remained poorly understood. In this study, with use of a variety of biochemical approaches including ge...

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Literature Corpus work: 1e10ca29-e9ce-5d3d-b8d8-1f3cbe88a67c
DOI: 10.21203/rs.3.rs-157614/v1

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