Article
Biomimetic Apoptotic Nanovesicles Derived from T Cells Target Neuroinflammation and Enhance Neural Regeneration via TGFBR2-Mediated Signaling for Spinal Cord Injury Repair
2026-04-09
Abstract excerpt
<title>Abstract</title> <p>Spinal cord injury (SCI) remains a major clinical challenge because persistent neuroinflammation and limited intrinsic regeneration jointly impede functional recovery. Here, biomimetic apoptotic nanovesicles (Apo-nanovesicles) derived from early apoptotic Jurkat T cells are developed as a cell-free nanotherapeutic platform for SCI repair. The Apo-nanovesicles retain apoptosis-associated...
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Identifiers and source
- Literature Corpus work
- 1dffa223-f643-5e0c-92af-e010cb066f49
- DOI
- 10.21203/rs.3.rs-9240762/v1
