Article

Downregulation of CAMK2N1 due to DNA Hypermethylation Mediated by DNMT1 Promotes the Progression of Prostate Cancer

2022-02-15

Abstract excerpt

<title>Abstract</title> <p>BackgroundCalcium/calmodulin-dependent protein kinase II inhibitor I (CAMK2N1) is one of the tumor suppressor genes in prostate cancer (PCa) and is significantly downregulated in PCa tissues compared to benign and normal prostate tissues. Reduced expression of CAMK2N1 is positively correlated with PCa progression. However, the mechanism of CAMK2N1 silencing in PCa is still unclear. The...

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Literature Corpus work: 1deba77f-1c47-5ab7-b86c-cc1697feff90
DOI: 10.21203/rs.3.rs-1323994/v1

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