Article

Curcumin combined with verapamil improve cardiovascular phenotype of a Williams-Beuren Syndrome mice model reducing oxidative stress

2022-12-20

Abstract excerpt

Williams-Beuren syndrome (WBS) is a rare neurodevelopmental disorder with hallmarks in the cardiovascular manifestations and no well-defined therapeutic strategies. We investigated the progression of cardiovascular phenotype present in CD (complete deletion) mice, a murine model of WBS, after chronic treatment with curcumin and verapamil, both compounds with positive effects on related pathologies. Treatment was a...

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Identifiers and source

Literature Corpus work: 1dd3557b-611c-5e18-9331-4cd02f6aa54c
DOI: 10.1101/2022.12.19.520405

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