Article
The Microsporidian Encephalitozoon Hellem Secretes A Host Nucleus-Targeting Protein (Ehhntp1) to Upregulate Endoplasmic Reticulum-Associated Degradation and Promote Protein Ubiquitination
2021-03-17
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>: Microsporidia, a group of obligate intracellular parasites that can infect humans and nearly all animals, have lost the pathways for de novo amino acid, lipid and nucleotide synthesis and instead evolved strategies to manipulate host metabolism and immunity. The endoplasmic reticulum (ER) is a vital organelle for producing and processing proteins and lipids and...
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Identifiers and source
- Literature Corpus work
- 1db1ba3d-c28e-52c6-bc6f-f28346dbf8f7
- DOI
- 10.21203/rs.3.rs-319485/v1
