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A Plastid Protein That Evolved from Ubiquitin and Is Required for Apicoplast Protein Import in <i>Toxoplasma gondii</i>

28 Jun 2017

Abstract excerpt

ABSTRACT Apicomplexan parasites cause a variety of important infectious diseases, including malaria, toxoplasma encephalitis, and severe diarrhea due to Cryptosporidium . Most apicomplexans depend on an organelle called the apicoplast which is derived from a red algal endosymbiont. The apicoplast is essential for the parasite as the compartment of fatty acid, heme, and isoprenoid biosynthesis. The majority of the...

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PMID: 28655825
DOI: 10.1128/mbio.00950-17

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