Article

Phenotypic exploration of Mice with a Point Mutation in BRAT1

2025-05-19

Abstract excerpt

<title>Abstract</title> <p>Background BRAT1 (BRCA1-associated ataxia telangiectasia mutated activator 1) plays a crucial role in several vital biological processes, including the DNA damage response and the maintenance of mitochondrial homeostasis. Dysfunction in BRAT1 leads to a range of clinical phenotypes, with the majority of affected individuals succumbing before reaching one year of age. Results Through a...

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Literature Corpus work: 1d5f9477-523e-506d-a2fe-cebcdb359209
DOI: 10.21203/rs.3.rs-6434862/v1

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