Article

A mouse model of autosomal dominant spastic ataxia and myopathy caused by a mutation in <i>Tuba4a</i>

2026-03-09

Abstract excerpt

<h4>ABSTRACT</h4> Hereditary ataxias are a heterogeneous group of neurodegenerative disorders characterized by impaired balance and coordination, often due to cerebellar dysfunction. Despite advances in identifying genetic causes, animal models remain essential for dissecting underlying mechanisms and testing therapeutic strategies. Here we describe a mouse model of spastic ataxia and myopathy caused by a missens...

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Identifiers and source

Literature Corpus work: a47ae005-034f-51a8-a8c9-0f0b72809183
DOI: 10.64898/2026.03.06.710113

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