Article

Association between schizophrenia and both loss of function and missense mutations in paralog conserved sites of voltage-gated sodium channels

2018-01-12

Abstract excerpt

Sequencing studies have highlighted candidate sets of genes involved in schizophrenia, including activity-regulated cytoskeleton-associated protein (ARC) and N-methyl-d-aspartate receptor (NMDAR) complexes. Two genes, SETD1A and RBM12 , have also been associated with robust statistical evidence. Larger samples and novel methods for identifying disease-associated missense variants are needed to reveal novel genes...

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Literature Corpus work: 1d4f1062-01d5-5629-baf8-543596a68609
DOI: 10.1101/246850

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