Article
Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages
2019-01-09
Abstract excerpt
Laterality defects are developmental disorders resulting from aberrant left/right patterning. In the most severe cases, such as in heterotaxy, they are associated with complex malformations of the heart. Advances in understanding the underlying physiopathological mechanisms have been hindered by the lack of a standardised and exhaustive procedure in mouse models, for phenotyping left/right asymmetries of all visce...
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Identifiers and source
- Literature Corpus work
- 1d2a430a-22ee-5e22-80cf-eed5fbb029b9
- DOI
- 10.1101/516039