Article
A novel 3D mouse embryo atlas based on micro-CT.
Development (Cambridge, England) - 1 Sept 2012
Wong Michael D, Dorr Adrienne E, Walls Johnathon R, Lerch Jason P, Henkelman R Mark
Abstract excerpt
The goal of the International Mouse Phenotyping Consortium (IMPC) is to phenotype targeted knockout mouse strains throughout the whole mouse genome (23,000 genes) by 2021. A significant percentage of the generated mice will be embryonic lethal; therefore, phenotyping methods tuned to the mouse embryo are needed. Methods that are robust, quantitative, automated and high-throughput are attractive owing to the...
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