Article
Elovanoid 34 Reduces Proinflammatory Cytokines and Arrest the Expression of Genes That Drive Senescence, Autophagy, Unfolded Protein Response (UPR), Matrix Metalloproteinases (MMPs) and Inflammation in Human Nasal Cells Exposed to House Dust Mite (HDM): Therapeutic Potential in Allergy
2021-03-26
Abstract excerpt
Elovanoids (ELV) are novel lipid mediators synthesized from very long-chain (VLC) omega-3 (n-3) polyunsaturated fatty acids (PUFA), particularly docosahexaenoic acid (DHA) or eicosa-pentaenoic acid (EPA), by the elongase enzyme ELOVL4. ELV have been shown to play a funda-mental role in maintaining brain and retina function, neuroprotection, maintaining the skin's permeability barrier, and sperm function, among oth...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 1cf9b44f-0284-546e-b2e9-f1dd2793a540
- DOI
- 10.20944/preprints202103.0663.v1
