Article

The +57C>T substitution in microRNA-184 is associated with microphthalmia, retinal detachment, and altered ocular development

2026-06-29

Abstract excerpt

<h4>Purpose</h4> To expand the clinical and mechanistic understanding of the +57C>T seed-region mutation in miR-184 causing EDICT (endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning) syndrome. <h4>Design</h4> Cross-sectional analysis and laboratory confirmation <h4>Participants</h4> 18 members of a four-generation family with known +57C>T miR-184 status <h4>Methods</h4> We used o...

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Literature Corpus work: 1cd14182-5f74-5a55-94b4-ccdcb2b5d62f
DOI: 10.64898/2026.06.25.26355554

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