Article
Mutational Analysis of Pre-miR-184 and hsa-mir-568 in Greek Patients With Sporadic Keratoconus.
Cornea - 1 May 2016
Moschos Marilita M, Droutsas Konstantinos, Sioziou Anna, Dettoraki Maria, Gazouli Maria
Abstract excerpt
PURPOSE: Despite numerous studies, the causes of keratoconus (KC) remain indefinable. Recently, polymorphisms in the seed region of miR-184 have been identified in familial severe KC and stromal thinning (endothelial dystrophy, iris hypoplasia, congenital cataract, and stromal thinning [EDICT]) syndrome. In this study, we conducted genotyping of microRNA genes localized in the reported KC loci, in a well-defined...
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