Article

Dysregulation of Alternative Splicing was Associated with the Pathogenesis of Ulcerative Colitis

2021-09-22

Abstract excerpt

<h4>Background: </h4> Although numerous risk loci of Ulcerative Colitis (UC) in the human genome have been identified, the pathogenesis of UC remains not fully understood. Recently, multiple transcriptomic analyses have shown that aberrant gene expression in UC patients’ colon tissues were associated with the disease progressing. A pioneer study also demonstrated that altered post-transcriptional regulation may be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1ccd7fac-3fa3-5b60-b54a-b4c598246bf8
DOI: 10.21203/rs.3.rs-827726/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dysregulation of Alternative Splicing was Associated with the Pathogenesis of Ulcerative ColitisDOI 10.21203/rs.3.rs-827726/v1Read

Alternative Splicing Signature in human Crohn’s DiseaseSemantic proximity Read

Multi-ancestry genome-wide and transcriptome-wide association analyses identified new risk loci and genes for inflammatory bowel diseaseSemantic proximity Read

Colonic Mucosal Transcriptomic Changes in Patients with Long-Duration Ulcerative Colitis Revealed Colitis-Associated Cancer PathwaysSemantic proximity Read

Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing dataSemantic proximity Read

Identification of genes critical for inducing ulcerative colitis and exploring their tumorigenic potential in human colorectal carcinomaSemantic proximity Read

Key common genes and pathways in ulcerative colitis and ankylosing spondylitis based on bioinformatics analysisSemantic proximity Read

Increased SERPINA3 Level Is Associated with Ulcerative ColitisSemantic proximity Read

Alternative splicing of DNA damage response genes and gastrointestinal cancers.Semantic proximity Read

Alternative Splicing Events in Tumor Immune Infiltration in Colorectal CancerSemantic proximity Read

Identification and analysis of key genes associated with ulcerative colitis based on DNA microarray data.Semantic proximity Read

Genome-Wide Profiling of Alternative Splicing Signature Reveals Prognostic Predictor for Esophageal CarcinomaSemantic proximity Read

Novel insight into the gene etiology of ulcerative colitis gained from transcriptome association study and single cell sequence analysisSemantic proximity Read