Article

Protein Lactylation and Metabolic Regulation of the Zoonotic Parasite <i>Toxoplasma gondii</i>

2022-05-20

Abstract excerpt

The biology of Toxoplasma gondii , the causative pathogen of one of the most wide-spread parasitic diseases remains poorly understood. Lactate, which is derived from glucose metabolic pathways, is considered to be not only an energy source in a variety of organisms including Toxoplasma gondii , but also a regulatory molecule that participates in gene activation and protein functioning. Lysine lactylation is a ty...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24a5d5bb-569a-5863-8064-ded5900c422b
DOI: 10.1101/2022.05.19.492655

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Protein Lactylation and Metabolic Regulation of the Zoonotic Parasite <i>Toxoplasma gondii</i>DOI 10.1101/2022.05.19.492655Read

Global Lysine Crotonylation and 2-Hydroxyisobutyrylation in Phenotypically Different Toxoplasma gondii ParasitesSemantic proximity Read

Lysine Acetylation Is Widespread on Proteins of Diverse Function and Localization in the Protozoan Parasite Toxoplasma gondiiSemantic proximity Read

Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligaseSemantic proximity Read

Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondiiSemantic proximity Read

m6A RNA methylation facilitates pre-mRNA 3’-end formation and is essential for viability of <i>Toxoplasma gondii</i>Semantic proximity Read

Proteomics Applications in Toxoplasma gondii: Unveiling the Host–Parasite Interactions and Therapeutic Target DiscoverySemantic proximity Read

<i>Toxoplasma gondii</i> PPM3C, a secreted protein phosphatase, affects parasitophorous vacuole effector exportSemantic proximity Read

Enabling tools for <i>Toxoplasma</i> glycobiologySemantic proximity Read

<i>In Vivo</i> Biotinylation of the <i>Toxoplasma</i> Parasitophorous Vacuole Reveals Novel Dense Granule Proteins Important for Parasite Growth and PathogenesisSemantic proximity Read

A bioinformatic approach for the prediction and functional classification of <i>Toxoplasma gondii</i> long non-coding RNAsSemantic proximity Read

GCN5a is a telomeric lysine acetyltransferase whose loss primes <i>Toxoplasma gondii</i> for latencySemantic proximity Read

Function and mechanism of lactylation in health and diseases: a comprehensive reviewSemantic proximity Read