Article

Direct therapeutic effect of sulfadoxine-pyrimethamine on nutritional deficiency-induced enteric dysfunction in a human intestine chip

2023-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Sulfadoxine-pyrimethamine (SP) antimalarial therapy has been suggested to improve the birth weight of infants in pregnant women in sub-Saharan Africa independently of malarial infection. Here, we investigated whether SP could have a direct impact on improving intestinal function, thereby enhancing the absorption of essential fats and nutrients crucial for fetal growth. Using a human organ-on-a-ch...

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Literature Corpus work: b412a2b0-52ed-5703-b10f-3c0b254da144
DOI: 10.1101/2023.07.13.23292620

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