Article

Proteogenomic view of cancer epigenetics: the impact of DNA methylation on the cancer proteome

2018-06-06

Abstract excerpt

Aberrant DNA methylation disrupts normal gene expression in cancer and broadly contributes to oncogenesis. We previously developed MethylMix, a model-based algorithmic approach to identify epigenetically regulated driver genes. MethylMix identifies genes where methylation likely executes a functional role by using transcriptomic data to select only methylation events that can be linked to changes in gene expressio...

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Literature Corpus work: 1c152bdc-586c-539a-bce0-9b2e54409a9b
DOI: 10.1101/340760

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