Back to search

Article

Characterization of Tumor-Associated Endothelial Cells and the Development of a Prognostic Model in Pancreatic Ductal Adenocarcinoma

2023-07-25

Abstract excerpt

<h4>Background</h4> Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by a complex tumor microenvironment. Angiogenesis is of paramount importance in the proliferation and metastasis of PDAC. However, currently, there are no well-defined biomarkers available to guide the prognosis and treatment of PDAC. <h4>Results</h4> In this study, we investigated the interactions between...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1b71f8e5-726a-5e3a-9290-d0f912ecb144
DOI
10.1101/2023.07.22.550139
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Characterization of Tumor-Associated Endothelial Cells and the Development of a Prognostic Model in Pancreatic Ductal AdenocarcinomaDOI 10.1101/2023.07.22.550139
Comprehensive characterization of extracellular matrix-related genes in PAAD identified a novel prognostic panel related to clinical outcomes and immune microenvironment: A silico analysis with in vivo and vitro validationSemantic proximity
The Heterogeneity of the Tumor Microenvironment as Essential Determinant of Development, Progression and Therapy Response of Pancreatic CancerSemantic proximity
Identification of stromal microenvironment characteristics and key molecular mining in pancreatic cancerSemantic proximity
Prognostic Significance and Immune Infiltration of Microenvironment‐related Signatures in Pancreatic CancerSemantic proximity
Bioinformatics analysis identified MMP14 and COL12A1 as immune-related biomarkers associated with pancreatic adenocarcinoma prognosisSemantic proximity
The Role of S100A9 in the Interaction Between Pancreatic Ductal Adenocarcinoma Cells and Stromal CellsSemantic proximity
High-Dimensional Protein Analysis Uncovers Distinct Immunological and Stromal Signatures Between Primary and Metastatic Pancreatic Ductal AdenocarcinomaSemantic proximity
Extravascular coagulation stabilizes pro-fibrotic stromal states via tumor-intrinsic PAR1 signaling in pancreatic ductal adenocarcinomaSemantic proximity
Novel targets identified by integrated cancer-stromal interactome analysis of pancreatic adenocarcinomaSemantic proximity
Preserved correlation matrices pinpoint extracellular matrix organization as a critical factor in pancreatic ductal adenocarcinomaSemantic proximity
In-depth proteomic profiling of the extracellular matrix of pancreatic ductal adenocarcinomas identifies signatures correlating with lymphocyte infiltrationSemantic proximity
Tumor Microenvironment in Pancreatic Cancer Pathogenesis and Therapeutic ResistanceSemantic proximity
Select a neighboring publication to make it the new centre.