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Preserved correlation matrices pinpoint extracellular matrix organization as a critical factor in pancreatic ductal adenocarcinoma

2023-04-18

Abstract excerpt

<h4>Background: </h4> Gene co-expression correlations frequently signal shared biological functions with coordinated regulation. We hypothesized that maintained correlations might be essential for cellular survival, representing potential vulnerabilities of cancer cells. We aimed to reveal correlations preserved in pancreatic ductal adenocarcinomas (PDAC) across normal and tumor tissues. <h4>Methods: </h4>: We se...

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Literature Corpus work
45b24731-a0a0-5199-9f59-e61ef58ecc20
DOI
10.12688/f1000research.131414.1
Open publication

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Preserved correlation matrices pinpoint extracellular matrix organization as a critical factor in pancreatic ductal adenocarcinomaDOI 10.12688/f1000research.131414.1
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