Article

Distinct organ-specific metastatic potential of individual breast cancer cells and primary tumors

2005-01-03

Abstract excerpt

We used bioluminescence imaging to reveal patterns of metastasis formation by human breast cancer cells in immunodeficient mice. Individual cells from a population established in culture from the pleural effusion of a breast cancer patient showed distinct patterns of organ-specific metastasis. Single-cell progenies derived from this population exhibited markedly different abilities to metastasize to the bone, lung...

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Identifiers and source

Literature Corpus work: 1b115c17-af08-5066-a20c-71c5c466cc84
DOI: 10.1172/jci200522320

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