Back to search

Article

Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL <sup>+</sup> - <i>Staphylococcus aureus</i> infections

2021-11-26

Abstract excerpt

Staphylococcus aureus ( S. aureus ) strains that produce the toxin Panton-Valentine leukocidin (PVL; PVL-SA) frequently cause recurrent skin and soft tissue infections (SSTI). PVL binds to and kills human neutrophils, resulting in the formation of neutrophil extracellular traps, but the pathomechanism has not been extensively studied. Furthermore, it is unclear why some individuals colonized with PVL-SA suffer fr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1aab2b4f-a11a-594e-8e71-65c8ad05b6cc
DOI
10.1101/2021.11.26.470012
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL <sup>+</sup> - <i>Staphylococcus aureus</i> infectionsDOI 10.1101/2021.11.26.470012
Molecular Prerequisites for Neutrophil Extracellular Trap Formation and Evasion Mechanisms of Staphylococcus aureusSemantic proximity
Development of a New N-Terminomic Method to Study the Pathodegradome of the <i>Staphylococcus aureus</i> V8 Protease in Human NeutrophilsSemantic proximity
Lipoproteins from Staphylococcus aureus Drive Neutrophil Extracellular Trap Formation in a TLR2/1- and PAD-Dependent Manner.Semantic proximity
Studying Staphylococcal Leukocidins: A Challenging EndeavorSemantic proximity
Identification of a Novel Staphylococcus aureus Two-Component Leukotoxin Using Cell Surface ProteomicsSemantic proximity
The mupA-Encoded Isoleucyl-tRNA Synthetase Suggests a Potential Link to Panton-Valentine Leukocidin in Staphylococcus aureusSemantic proximity
Staphylococcus aureus Elaborates Leukocidin AB To Mediate Escape from within Human NeutrophilsSemantic proximity
Staphylococcus aureus senses human neutrophils via PerR to coordinate the expression of the toxin LukABSemantic proximity
Mucoricin binding to β-glucan sites on germinating Mucorales spores disrupts neutrophil swarming to promote pathogenicitySemantic proximity
New Aspects of the Biology of Neutrophil Extracellular TrapsSemantic proximity
Aging hampers neutrophil extracellular traps (NETs) efficacySemantic proximity
NETs By-products and Extracellular DNA May Play a Key Role in COVID-19 Pathogenesis: Incidence on Patient Monitoring and TherapySemantic proximity
Select a neighboring publication to make it the new centre.