Article

Coenzyme Q10 Loaded DQAsomes for Leigh Disease

2023-10-03

Abstract excerpt

Leigh syndrome (LS), a rare hereditary neurometabolic disorder caused by mitochondrial dysfunction, results from genetic mutations affecting the central nervous system. Endogenous bioactive antioxidant Coenzyme Q10 (CoQ10) deficiency is associated with LS and contributes to various clinical symptoms. Dequalinium chloride (DQA) is a bolalipid with mitochondria-targeting properties. This study aimed to develop CoQ10...

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Literature Corpus work: 1aa71473-a141-5bb3-93c3-c6171c5762da
DOI: 10.21203/rs.3.rs-3370616/v1

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