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Mixed infections and heteroresistance of Mycobacterium tuberculosis among multidrug-resistant tuberculosis in China: a genomic epidemiology study

1 Aug 2025

Abstract excerpt

Mixed infection refers to the presence of multiple Mycobacterium tuberculosis strains within one host, while heteroresistance denotes the coexistence of drug-susceptible and drug-resistant strains or genotypes. Mixed infections and heteroresistance with Mycobacterium tuberculosis can complicate drug resistance diagnosis, treatment options, and transmission inference. We conducted a population-based genomic...

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PMID: 40748858
DOI: 10.1080/22221751.2025.2534656

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