Article

Bovine AAV - a promising vector for pulmonary gene therapy

2026-07-15

Abstract excerpt

Efficient systemic delivery to the lung remains a major barrier for adeno-associated virus (AAV)-mediated pulmonary gene therapy, particularly when pre-existing immunity limits the use of conventional capsids. Here, we evaluated Bovine AAV, a phylogenetically divergent capsid, as candidate vector for lung-directed gene transfer. In adult C57BL/6J mice, intravenous delivery of Bovine AAV resulted in robust and pref...

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Literature Corpus work: 18b6de37-fab3-5134-bcca-ab72b800bc7c
DOI: 10.64898/2026.07.14.738418

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