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Pattern-Based Genome Mining Guides Discovery of the Antibiotic Indanopyrrole A from a Marine Streptomycete

22 Nov 2024

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Terrestrial actinomycetes in the genus Streptomyces have long been recognized as prolific producers of small-molecule natural products, including many clinically important antibiotics and cytotoxic agents. Although Streptomyces can also be isolated from marine environments, their potential for natural product biosynthesis remains underexplored. The MAR4 clade of...

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PMID: 39575834
DOI: 10.1021/acs.jnatprod.4c00934

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