Article

Circumstantial Evidence? Comparison of Statistical Learning Methods using Functional Annotations for Prioritizing Risk Variants

2014-11-15

Abstract excerpt

Although technology has triumphed in facilitating routine genome re-sequencing, new challenges have been created for the data analyst. Genome scale surveys of human disease variation generate volumes of data that far exceed capabilities for laboratory characterization, and importantly also create a substantial burden of type I error. By incorporating a variety of functional annotations as predictors, such as regul...

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Identifiers and source

Literature Corpus work: 1888ef55-c94c-5851-b7ab-c71e3903bded
DOI: 10.1101/011445

Open publication

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