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Article

Prioritization Of Nonsynonymous Single Nucleotide Variants For Exome Sequencing Studies Via Integrative Learning On Multiple Genomic Data.

Scientific reports - 13 Oct 2015

Wu Mengmeng, Wu Jiaxin, Chen Ting, Jiang Rui

Abstract excerpt

The rapid advancement of next generation sequencing technology has greatly accelerated the progress for understanding human inherited diseases via such innovations as exome sequencing. Nevertheless, the identification of causative variants from sequencing data remains a great challenge. Traditional statistical genetics approaches such as linkage analysis and association studies have limited power in analyzing...

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PMID: 26459872
DOI: 10.1038/srep14955
PMCID: PMC4602202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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