Article

A Phylogeny-Based Approach to Discover Mutational Processes in Primates

2024-12-05

Abstract excerpt

The accumulation of germline mutations underpins population diversity and drives genetic evolution. Despite the availability of extensive phylogenetic data, the lack of suitable methodologies has hindered the comprehensive characterization of germline mutational processes across evolutionary trees. To address this, we develop a robust three-step methodology that extracts germline mutational processes from alignmen...

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Literature Corpus work: 18466e17-9cfe-5820-9a8f-640986776184
DOI: 10.1101/2024.12.02.626204

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