Article

“Evolution of the mutation spectrum across a mammalian phylogeny”

2023-06-01

Abstract excerpt

Little is known about how the spectrum and etiology of germline mutagenesis might vary among mammalian species. To shed light on this mystery, we quantify variation in mutational sequence context biases using polymorphism data from thirteen species of mice, apes, bears, wolves, and cetaceans. After normalizing the mutation spectrum for reference genome accessibility and k -mer content, we use the Mantel test to d...

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Literature Corpus work: e9df7b82-f15c-5e3d-a0be-5b5c4f1dcb3d
DOI: 10.1101/2023.05.31.543114

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