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From Immunosenescence to Aging Types – Establishing Reference Intervals for Immune Age Biomarkers by Centile Estimation

2023-08-07

Abstract excerpt

Immunological aging type definition requires establishing reference intervals from the distribution of immunosenescence biomarkers conditional on age. For 1,605 individuals (18–97 years), we determined the comprehensive IMMmune Age indeX IMMAX from flow cytometry-based blood cell sub-populations, and identified age-specific centiles by fitting generalized additive models for location, scale and shape. The ce...

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Literature Corpus work
1843df8d-2d58-5e3b-8e8d-e7bc8730a9cb
DOI
10.20944/preprints202308.0524.v1
Open publication

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