Article
The human immunosenescence phenotype: does it exist?
Seminars in immunopathology - 1 Oct 2020
Pawelec Graham
Abstract excerpt
"Immunosenescence" has been invoked as the root cause of increased incidence and severity of infectious disease in older adults and their poorer response to vaccination, and is implicated in increased solid cancers and increased autoimmunity with age. But how to define it in the individual and to show that immunosenescence is responsible for these adverse health outcomes? How can we monitor interventions aimed at...
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