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Ultrasensitive tumour‐agnostic non‐invasive detection of colorectal cancer recurrence using ctDNA methylation

1 Sept 2022

Abstract excerpt

Dear Editor, Colorectal cancer (CRC) is the third most common cancer (10.0%) and the second leading cause of cancer-related deaths (9.4%) worldwide.1 Here we show cancer-derived DNA methylation (DNAm) enables sensitive and specific non-invasive diagnosis and monitoring of CRC. Cell-free DNA (cfDNA) containing tumour-derived biomarkers provide a promising avenue for non-invasive detection of minimal residual...

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PMID: 36103400
DOI: 10.1002/ctm2.1015

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