Article

Extracellular vesicles from deciduous pulp stem cells recover bone loss by regulating telomerase activity in an osteoporosis mouse model

2020-06-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Systemic transplantation of stem cells from human exfoliated deciduous teeth (SHED) recover bone loss in animal models of osteoporosis; however, the mechanisms underlying this remain unclear. Here, we hypothesized that trophic factors within SHED-releasing extracellular vesicles (SHED-EVs) rescue osteoporotic phenotype. <bold>Methods: </bold>EVs were isolated fr...

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Literature Corpus work: f5c1b830-0dab-5ab5-8400-16ae977ea704
DOI: 10.21203/rs.3.rs-20407/v2

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