Article

The gut microbiome promotes mitochondrial respiration in the brain of a Parkinson’s disease mouse model

2024-12-21

Abstract excerpt

<h4>ABSTRACT</h4> The pathophysiology of Parkinson’s disease (PD) involves gene-environment interactions that impair various cellular processes such as autophagy, lysosomal function, or mitochondrial dysfunction. Specifically, mitochondria-associated gene mutations increase PD risk, mitochondrial respiration is altered in the PD brain, and mitochondrial-damaging toxins cause PD-like motor and gastrointestinal sym...

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Identifiers and source

Literature Corpus work: 17cb2670-6bc5-5130-a81a-e61279647160
DOI: 10.1101/2024.12.18.629251

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