Article

Neuroproteomics and systems biology-based discovery of protein biomarkers for traumatic brain injury and clinical validation.

2008-10-01

Abstract excerpt

The rapidly growing field of neuroproteomics has expanded to track global proteomic changes underlying various neurological conditions such as traumatic brain injury (TBI), stroke, and Alzheimer's disease. TBI remains a major health problem with approximately 2 million incidents occurring annually in the United States, yet no affective treatment is available despite several clinical trials. The absence of brain in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 17a5cded-e491-52ae-887a-19aa6d92857f
DOI: 10.1002/prca.200800011

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Neuroproteomics and systems biology-based discovery of protein biomarkers for traumatic brain injury and clinical validation.DOI 10.1002/prca.200800011Read

Trajectories of blood-based protein biomarkers in chronic traumatic brain injurySemantic proximity Read

Neuroproteomics: Expression Profiling of the Brain's Proteomes in Health and DiseaseSemantic proximity Read

Proteomic analysis of ubiquitination modified proteins in brain tissue of rats at different times after severe traumatic brain injurySemantic proximity Read

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic ActivitySemantic proximity Read

MicroRNAs: The New Challenge for Traumatic Brain Injury DiagnosisSemantic proximity Read

Applying Systems Biology Methodology To Identify Genetic Factors Possibly Associated with Recovery after Traumatic Brain InjurySemantic proximity Read

Heterogeneity of acute traumatic brain injured patients: how to identify phenotypes and tailor specific treatment.Semantic proximity Read

Fluid Proteomics of CSF and Serum Reveal Important Neuroinflammatory Proteins in Blood-Brain Barrier Disruption and Outcome Prediction following Severe Traumatic Brain Injury: a Prospective, Observational StudySemantic proximity Read

Bioinformatic analysis of brain-specific miRNAs for identification of candidate traumatic brain injury blood biomarkersSemantic proximity Read

Unveiling the Role of PSD95 Phosphorylation after Traumatic Brain Injury: Insights from Phosphoproteomic AnalysisSemantic proximity Read

Discovery and development of biomarkers of neurological diseaseSemantic proximity Read

Biomarkers of neurodegeneration in post-traumatic stress disorder: an integrative reviewSemantic proximity Read